TABLE 2.

Hemodynamic measures in response to α-adrenergic and nitric oxide synthase (NOS) blockade before and after exercise training

		Baseline	α-adrenergic blockade	Combined α-adrenergic and NOS blockade
Heart rate, beats/min	Before	59 ± 4	70 ± 5†	61 ± 4†
	After	57 ± 4	71 ± 5†	54 ± 3*†‡
Brachial SBP, mmHg	Before	124 ± 6	109 ± 5†	133 ± 9‡
	After	121 ± 6	103 ± 6†	127 ± 6‡
Brachial MAP, mmHg	Before	94 ± 6	79 ± 5†	96 ± 5‡
	After	93 ± 4	76 ± 4†	97 ± 5‡
Brachial DBP, mmHg	Before	72 ± 3	65 ± 3†	79 ± 5†‡
	After	70 ± 4	59 ± 4*†	75 ± 3‡
Brachial PP, mmHg	Before	52 ± 4	44 ± 3	54 ± 5
	After	50 ± 4	47 ± 3	53 ± 4
Carotid SBP, mmHg	Before	114 ± 7	100 ± 5†	122 ± 9‡
	After	112 ± 7	95 ± 6†	117 ± 6‡
Carotid PP, mmHg	Before	42 ± 5	35 ± 5	43 ± 5
	After	42 ± 5	36 ± 4	42 ± 5

Data are mean±SEM. SBP=systolic blood pressure, MAP=mean arterial pressure, DBP=diastolic blood pressure, PP=pulse pressure.

^*P<0.05 vs. before training

^†P<0.05 vs. baseline

^‡P<0.05 vs. α-adrenergic blockade.