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. Author manuscript; available in PMC: 2010 Sep 9.
Published in final edited form as: Structure. 2009 Sep 9;17(9):1253–1264. doi: 10.1016/j.str.2009.07.008

Figure 8.

Figure 8

Model for the dynamic instability of ParM filaments. ParM filament is shown as a stack of circles, where each circle represents a ParM protomer. Black circles represent ParM-ATP; grey circles represent ParM-ADP, and black circles with deleted center stand for the intermediate ParM-ADP-Pi state. Shortly after polymerization ParM filament is comprised of ATP subunits (A), which over time turn into ADP-Pi state (B) followed by the ADP state (C). The integrity of the filament in (A-C) is preserved by the ATP-cap. Inorganic phosphate release inhibits the formation of the protective ATP-cap (D). Finally, the ADP subunits are exposed (E), and the filament depolymerizes (F).