Table 6.
Independent predictors of cortical hand bone loss, results from multivariate logistic regression analyses
| One-year cortical hand bone loss | Two-year cortical hand bone loss | Five-year cortical hand bone loss | ||||
| OR (95% CI) |
P value | OR (95% CI) |
P value | OR (95% CI) |
P value | |
| Anti-CCP (> 25 U/ml) | 2.2 (1.0 to 4.5) |
0.04 | 2.6 (1.1 to 6.2) |
0.03 | 4.9 (1.4 to 16.7) |
0.01 |
| ESR (> 20 mm/h) | 4.5 (2.0 to 9.9) |
< 0.001 | 3.5 (1.3 to 9.3) |
0.01 | ||
| Prednisolone use | 4.7 (1.6 to 14.1) |
0.006 | ||||
| Age (years) | 1.0 (0.9 to 1.0) |
0.62 | 1.0 (0.9 to 1.1) |
0.23 | 1.1 (1.0 to 1.1) |
0.89 |
| Sex (female) | 1.0 (0.4 to 2.4) |
0.95 | 0.5 (0.2 to 1.3) |
0.14 | 0.9 (0.2 to 3.4) |
0.02 |
| Constant | 0.5 | 0.35 | 0.4 | 0.37 | 0.3 | 0.31 |
Final models after multivariate logistic regression analyses. Dependent variable: cortical hand bone loss (yes/no). Anti-CCP = antibodies to cyclic citrullinated peptide; CI = confidence interval; ESR = erythrocyte sedimentation rate; OR = odds ratio.