Table 1.
Acute phase (day 3) | Remission phase (days 10 and 11) | Chronic phase (days 24 to 30) | ||||
SCW + PBS | SCW + Apo | SCW + PBS | SCW + Apo | SCW + PBS | SCW + Apo | |
AI scorea | 4.2 ± 0.8 | 2.0 ± 0.6 | 1.7 ± 0.7 | 0.5 ± 0.7 | 4.9 ± 3.5 | 1.3 ± 1.4 |
n | 12 | 13 | 5 | 6 | 5 | 6 |
P valueb | 0.041 | 0.052 | 0.030 | |||
Incidencec | 10/12 | 7/13 | 4/5 | 2/6 | 5/5 | 3/6 |
Pooled results from of three independent experiments. n, number of rats. aArticular index score presented as mean ± standard error of the mean. bCompared between streptococcal cell wall (SCW) and SCW + apoptotic cells (Apo); Mann-Whitney rank-sum test, one tail. cNumber of rats with disease among the rats of each group; the lower number of animals in the chronic phase is due to sacrifice of animals at the end of the acute phase in some experiments.