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. 2009 Jul 2;11(4):R104. doi: 10.1186/ar2750

Table 1.

Apoptotic cell injection prevents rats from SCW-induced arthritis development

Acute phase (day 3) Remission phase (days 10 and 11) Chronic phase (days 24 to 30)



SCW + PBS SCW + Apo SCW + PBS SCW + Apo SCW + PBS SCW + Apo
AI scorea 4.2 ± 0.8 2.0 ± 0.6 1.7 ± 0.7 0.5 ± 0.7 4.9 ± 3.5 1.3 ± 1.4
n 12 13 5 6 5 6
P valueb 0.041 0.052 0.030
Incidencec 10/12 7/13 4/5 2/6 5/5 3/6

Pooled results from of three independent experiments. n, number of rats. aArticular index score presented as mean ± standard error of the mean. bCompared between streptococcal cell wall (SCW) and SCW + apoptotic cells (Apo); Mann-Whitney rank-sum test, one tail. cNumber of rats with disease among the rats of each group; the lower number of animals in the chronic phase is due to sacrifice of animals at the end of the acute phase in some experiments.