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. 2009 Jul 16;11(4):R110. doi: 10.1186/ar2765

Table 5.

Odds ratios for having the metabolic syndrome in patients receiving methotrexate compared with those not on methotrexate

Odds ratio 95% confidence interval P value
Crude 0.483 0.32 to 0.73 0.001
Model a 0.505 0.33 to 0.77 0.001
Model b 0.525 0.34 to 0.80 0.003
Model c 0.517 0.33 to 0.80 0.004

Crude = unadjusted model

Model a = adjusted for age and sex

Model b = adjusted for age, sex, disease duration, erythrocyte sedimentation rate and health assessment questionnaire score

Model c = adjusted for age, sex, disease duration, erythrocyte sedimentation rate, health assessment questionnaire score, sulphasalazine, hydroxyxhloroquine, leflunomide, anti-tumour necrosis factor therapy, glucocorticoid use and NSAID use.