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Short- and long-term changes of RF levels in PB after rituximab treatment. (a) Rheumatoid factor (RF)-levels in peripheral blood (PB) at day 0, 3 and 6 months after rituximab treatment. (b) RF-levels in PB comparing rituximab-naïve and treated patients. Box represents 25th to 75th percentile, line indicates median, whereas error bars represent range. Statistical evaluation was performed using paired t-test (short-term changes) and Mann-Whitney t-test (long-term changes).
