Table 5.
Absolute numbers of B cells in bone marrow (per 106 mononuclear cells)
| Long-term |
CD27-IgD- (Immature) |
CD27-IgD+ (Naïve) |
CD27+IgD+ (Unswitched) |
CD27+IgD- (Switched) |
Total number of CD19+ cells |
| RTX-naïve n = 24 |
185 ± 247 (32%) |
206 ± 134 (36%) |
35 ± 44 (6%) |
148 ± 94 (26%) |
574 ± 129 (100%) |
| RTX-treated n = 13 |
260 ± 251 (51%) P = ns |
174 ± 147 (34%) P = ns |
4 ± 3 (1%) P = 0.0009 |
68 ± 72 (13%) P = 0.001 |
506 ± 118 (100%) |
* Values are given as mean ± standard deviation.
** Statistics are calculated with paired T-test, P-values are given in comparison to day 0.
RTX = rituximab.