Table 2. Docking Success Depends on Docking Parameters^a.

parameter choice	DOCK score	ScreenScore	FlexX	PLP	PMF
all	18	18	16	18	10
any	29	36	33	38	22

^aSuccess is defined as ligand within 2 Å RMSD of the crystal pose and rank in the top 5% of about 100 property-matched decoys. Astex-85 benchmark. For instance, whereas 29 targets succeeded for pose fidelity and rank using any of four parameter sets and the standard DOCK scoring function, only 18 of these succeeded with all parameter sets.