Table 3.
Description | Controls | IBS (n = 10) | P-value (n = 10) | |
---|---|---|---|---|
Age (years ± SEM) | 33.9 ± 3.5 | 40 ± 2.3 | ns | |
BMI (±SEM) | 25.5 ± 1.7 | 28.6 ± 2.7 | ns | |
Symptom severity | IBS symptom severity (0–20 cm) | – | 13.5 ± 1.5 | |
Abdominal pain | Chronic abdominal pain (unpleasantness) | – | 12.4 ± 0.8 | |
Chronic abdominal pain (intensity) | – | 14.1 ± 0.6 | ||
Current abdominal pain (unpleasantness) | – | 11.7 ± 1.2 | ||
Current abdominal pain (intensity) | – | 13.1 ± 1.1 | ||
Gynaecological history (n) | ||||
Premenopausal phase | Follicular | 4 | 5 | ns |
Luteal | 4 | 4 | ||
Menses | 1 | 0 | ||
Postmenopausal | 1 | 1 | ns | |
Chronic stress indicators [n (%)] | Childhood abuse | 1 (10) | 2 (20) | ns |
Adult abuse | 0 (0) | 1 (10) | ns | |
Early adverse event | 0 (0) | 1 (10) | ns | |
HAD scores | Anxiety | 2.22 ± 0.43 | 5.2 ± 0.92 | 0.01 |
Depression | 0.33 ± 0.24 | 3.7 ± 0.97 | <0.01 |
BMI, body mass index. Chronic pain symptoms were rated over previous 1 month. Current pain was rated over previous 24 h. For premenopausal women not taking OCP, the menstrual cycle phase was determined by the count forward/backward method: menses, first 3 days of menses; follicular, days 4–14; luteal, day 14 onward and before menses.