Table 4.

Logistic regression analysis of substance use disorders among past-year drug users aged 18 years or older in the 2006 NSDUH (N = 8464)

AOR (95% CI)	Past-year drug use status			Age of first MDMA use
Substance use disordersa	Recent MDMA use vs. other drug use	Former MDMA use vs. other drug use	Recent MDMA use vs. former MDMA use	Before 18 years vs. never used	18–22 years vs. never used	23+ years vs. never used
Nicotineb	1.2 (0.9–1.5)	1.2 (1.0–1.5)	1.0 (0.7–1.4)	1.3 (1.0–1.7)d	1.1 (0.9–1.4)	1.2 (0.9–1.5)
Alcohol	1.2 (0.8–1.6)	0.8 (0.7–1.0)	1.4 (1.0–2.0)	1.0 (0.8–1.4)	1.0 (0.8–1.3)	0.8 (0.5–1.1)
Any drugc	2.2 (1.6–3.1)d	1.0 (0.7–1.3)	2.1 (1.5–3.0)d	1.2 (0.9–1.6)	1.4 (1.0–1.8)	1.2 (0.9–1.7)
Marijuana	2.4 (1.7–3.5)d	1.1 (0.8–1.4)	2.2 (1.5–3.2)d	1.2 (0.9–1.7)	1.4 (1.0–1.9)	1.7 (1.1–2.6)d
Cocaine/crack	1.6 (1.0–2.7)	0.9 (0.5–1.6)	1.8 (1.1–3.0)d	1.1 (0.7–1.7)	1.3 (0.7–2.4)	0.7 (0.4–1.5)
Hallucinogens	5.8 (2.7–12.7)d	0.5 (0.2–1.4)	12.0 (4.8–29.8)d	1.4 (0.5–3.9)	1.8 (0.8–4.1)	1.6 (0.4–6.7)
Pain relievers/opioids	2.0 (1.2–3.2)d	1.2 (0.8–1.9)	1.3 (0.8–2.3)	1.7 (1.2–2.4)d	1.2 (0.7–2.1)	0.7 (0.3–1.5)
Tranquilizers	2.1 (0.9–4.7)	0.8 (0.4–1.7)	2.7 (1.2–5.8)d	1.9 (0.7–5.1)	0.6 (0.3–1.4)	1.0 (0.3–3.5)

Note: The prevalence of stimulant, heroin, inhalant, and sedative use disorders was low; and each was not associated with MDMA use status. AOR = adjusted odds ratios; CI = confidence interval.

^aEach separate logistic regression model adjusted for gender, age, race/ethnicity, education, marital status, family income, population density, past-year major depressive episode, past-year anxiety disorder, age of first drug use, and history of polydrug use.

^bPast-month nicotine dependence; all others were past-year abuse of or dependence on that substance.

^cAny drug use disorder included abuse of or dependence on marijuana, cocaine, inhalants, hallucinogens, heroin, stimulants, pain relievers/opioids, sedatives, and tranquilizers.

^dp < 0.05.