Table 1.
Demographic and clinical characteristics. Figures represent mean (SD) unless stated otherwise.
Controls | rMDD patients | |
---|---|---|
N (male) | 20 (7) | 23 (6) |
Age | 30.5 (7.3) | 32.4 (9.8) |
IQ | 122.9 (10.5) | 127.1 (10.5) |
N with history of alcohol/substance abuse | 0 (0%) | 1 (4%) |
Number of depressive episodes | - | 2.7 (2.0) |
Number of first degree relatives with MDD | - | 1.0 (0.82) |
Age of onset of first depressive episode | - | 20.1 (8.4) |
Time since last treatment (months)1 | - | 24 (3-156) |
N with at least 2 depressive episodes | - | 17 (74%) |
N with hospitalization during depressive episode | - | 5 (22%) |
N previously attempting suicide | - | 5 (22%) |
Time in remission (months)1 | - | 18 (6-156) |
N with any past SSRI treatment2 | - | 19 (83%) |
Median (range)
Of the remaining subjects one had been treated exclusively with trimipramine, one exclusively with bupropion and two were treatment-naive