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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Biochem Pharmacol. 2009 Apr 1;77(7):1273–1282. doi: 10.1016/j.bcp.2008.12.028

Fig 4.

Fig 4

Serum alanine transaminase (ALT) levels in wild-type and Nrf2-null mice pretreated with oleanolic acid (90 mg/kg, i.p.) once daily for three days (n=5 for all groups except Nrf2-null mice receiving vehicle, n=4), administered acetaminophen (500 mg/kg, i.p.) on the fourth day, and sacrificed 8-h later. Units are in International Units/Liter (IU/L) expressed as mean ± S.E.M. A minus sign (-) represents that the animal was administered the appropriate vehicle for the compound specified. A plus sign (+) represents that the animal was administered the compound specified. Asterisks (*) indicate a statistically significant difference from wild-type mice receiving vehicle (p ≤ 0.05). Daggers (†) indicate a statistically significant difference from Nrf2-null mice receiving vehicle (p ≤ 0.05).