Table 6.
Diabetes management of EDIC cohort during the first 2 years of EDIC
| DCCT treatment group assignment |
|||
|---|---|---|---|
| Intensive | Conventional | P value | |
| n | 687 | 688 | — |
| Insulin delivery during EDIC | <0.0001 | ||
| CSII | 37.0 | 12.6 | |
| MDI | 57.6 | 56.9 | |
| One or two injections/day | 5.3 | 30.3 | |
| Unknown | 0.1 | 0.3 | — |
| Human insulin (% of subjects using) | 91.1 | 90.8 | NS |
| Insulin dose (U · kg−1 · day−1) | 0.75 ± 0.28 | 0.67 ± 0.20 | <0.0001 |
| Self-monitored blood glucose ≥4/day (%) | 46.4 | 36.4 | 0.0002 |
| Hypoglycemia (rate per 100 patient-years) | |||
| Coma/seizure | 6.3 | 7.1 | NS |
| Requiring assistance | 25.4 | 25.7 | NS |
| DKA (rate per 100 patient-years) | 2.68 | 2.37 | NS |
| Overweight (%) | |||
| Men | 32.5 | 29.7 | NS |
| Women | 38.4 | 25.2 | 0.0005 |
Data are means ± SD. P values are from the contingency-table χ2 test for categorical variables, Wilcoxon’s rank-sum test for continuous variables, and from a Wald test of the log-relative adjusted for overdispersion of event rates. Overweight is defined for men as BMI (kg/m2) >27.8 from the second National Health and Nutrition Examination Survey (NHANES II) of 1976 to 1980 (50) and for women as BMI (kg/m2) >27.3.