Skip to main content
. Author manuscript; available in PMC: 2010 Oct 2.
Published in final edited form as: Neurosci Lett. 2009 Jun 30;462(1):20–23. doi: 10.1016/j.neulet.2009.06.081

Figure 2.

Figure 2

A. Effects of α7 nAchRs antagonist MLA on the DMPP-induced responses. The raw recordings (top) show that pre-administration of MLA largely blocked the DMPP-induced sympathetic responses with no effect on the parasympathetic response. Mean data (bottom) show that compared with the treatment with DMPP alone (open bars), pre-administration of MLA (solid bars) significantly abolished the DMPP-induced pressor response and the increase in HR with no effect on the decrease in HR. B. Effects of α4β2 nAchRs antagonist DHβE on the DMPP-induced responses. Raw recordings (top) show that pre-administration of DHβE largely blocked the DMPP-induced parasympathetic response with no effect on the sympathetic response. Mean data (bottom) show that, compared with the DMPP alone (open bars), pre-administration of DHβE (solid bars) significantly attenuated the DMPP-induced decrease in heart rate with no effect on the pressor response and the increase in HR. “*” represents p<0.05 compared to the DMPP alone. n= 5