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. Author manuscript; available in PMC: 2009 Sep 17.
Published in final edited form as: Nature. 2008 Aug 21;454(7207):1000–1004. doi: 10.1038/nature07221

Figure 3. BMP-7 triggers commitment of mesenchymal progenitor cells to brown adipocyte lineage in vitro and in vivo.

Figure 3

a, Oil Red O staining and Western blotting analysis for UCP-1 in C3H10T1/2 cells treated with BMP-7 or vehicle (control) for 3 days followed by adipogenic induction for 7 days. β-tubulin serves as a loading control. b, c, Q-RT-PCR analysis for genes involved in adipogenic program (b) and mitochondrial biogenesis (c) in cells described in a. Data are presented as mean ± SEM (n = 3). d, UCP-1 immunohistochemical staining on a tissue derived from implantation of BMP-7-treated C3H10T1/2 cells into nude mice. Original magnification = 400 X.