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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Clin Cancer Res. 2009 Aug 25;15(17):5379–5388. doi: 10.1158/1078-0432.CCR-09-0265

Figure 2. The abscopal effect is induced in TSA tumor-bearing mice by fractionated radiation in combination with anti-CTL-4 antibody.

Figure 2

(A) Tumor growth delay of primary irradiated tumors (left panel) and secondary non-irradiated tumor (right panel) in mice treated with PBS (closed circles), 9H10 (open circles), 20 Gy × 1 + PBS (closed diamonds), 20 Gy × 1 + 9H10 (open diamonds), 8 Gy × 3 + PBS (closed squares), 8 Gy × 3 + 9H10 (open squares), 6 Gy × 5 + PBS (closed triangles), or 6 Gy × 5 + 9H10 (open triangles). 9H10 was given on days 14, 17, and 20. Data are the mean ± SE of 5 mice/group. (B) Tumor weight of primary (left panel) and secondary (right panel) tumors at day 35. Data are the mean ± SE. The number of mice with complete tumor regression over the total number of mice per group is indicated. Data shown are from one of two independent experiments with similar results.

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