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. Author manuscript; available in PMC: 2009 Sep 17.
Published in final edited form as: Org Lett. 2008 Mar 20;10(8):1657–1659. doi: 10.1021/ol800395m

Table 1.

Asymmetric Hydrovinylation of 4-Methoxystyrenea,b

entry ligand (mol %) conv (%) selec. (%) % eec confd
1 L1 + L2/0.7 >99 >99 0 -
2 L1/0.7 >99 >99 94 S
3 L2/0.7 >99 >99 >95 R
4 L3/0.7 >99 >99 94 S
5 L4/0.7 0 - - -
6 L5/0.7 23 >99 76 S
7 L5/2.0 87 >99 78 S
8 L6/0.7 21 >99 90 S
9 L6/2.0 >99 95 92 S
10 L7/2.0 14 >99 16 S
11 L8/0.7 2 >99 86 S
12 L8/1.0 2 >99 85 S
13 L8/2.0 21 >99 87 S
14 L9/0.7 73 >99 91 S
15 L9/1.0 >99 91 88 S
16 L9/2.0 >99 65 87 S
17 L10/0.7 >99 >99 98 S
a

See Supporting Information for full experimental details.

b

Conversions and selectivities determined by GC analysis.

c

GC on Cyclodex-B column.

d

Configuration assigned by comparison of GC retention times of known compounds.3