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. Author manuscript; available in PMC: 2009 Sep 17.
Published in final edited form as: Biochemistry. 2009 Jan 13;48(1):132–139. doi: 10.1021/bi8014423

Figure 4.

Figure 4

Crystallographic Structure of PMS-MIF Complex at 1.55Å. A. Global structure of the PMS-MIF complex. B, C, D. Active site with 4.5σ Fo-Fc electron density calculated omitting Pro 1 and the PMS moiety. The fit to the electron density is displayed in active site A and is similar in the other two active sites. B. View showing the tetrahedral character of the Pro 1 nitrogen. C. View showing phenyl ring of PMS in active site. D. Same as (C), but rotated 90°, showing the covalent bond between Pro 1 and the PMS moiety.