TABLE 2.
Mutation rates in rad27 mutants
| Strain | Mutation rate (×10−7 events/cell/generation) ± SDab |
|---|---|
| RAD27 | 1.1 ± 0.7 (1) |
| rad27-p | 1.2 ± 0.6 (1) |
| rad27Δ | 129 ± 77 (117) |
| rad27-K325* | 165 ± 50 (150) |
| rad27-A358* | 3.1 ± 1 (3) |
| rad27-pX8 | 18 ± 7 (17) |
Mutation to canavanine resistance for cells grown in YPD media is shown.
a
SD, standard deviation.
b
Values normalized to the RAD27 rate are shown in parentheses. All the rad27 mutants, apart from rad27-p, have mutation rates significantly higher (P < 0.05) than the wild-type rate.