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Dinucleotide repeat instability in rad27 alleles
| Strain | Mutation rate (×10−6 events/cell/generation) ± SDab |
|---|---|
| RAD27 | 1 ± 0.3 |
| rad27-p | 2 ± 1 |
| rad27Δ | 604 ± 309 |
| rad27-K325* | 810 ± 164 |
| rad27-A358* | 22 ± 1 |
| rad27-pX8 | 272 ± 21 |
Mutation to 5-FOA resistance for cells harboring pSH44 grown in omission media is shown.
SD, standard deviation.
All the rad27 mutants, apart from rad27-p, have mutation rates significantly higher (P < 0.05) than the wild-type rate.
