TABLE 4.

Mutation rates in rad27 mutants

	Mutation rate (×10−7 events/cell/generation) ± SDa
Strain	Empty vectorb	POL30b
RAD27	1.8 ± .3 (1)	2.3 ± 1 (1)
rad27Δ	257 ± 65 (143)	31 ± 4 (13)
rad27-K325*	134 ± 22 (74)	36 ± 9 (16)
rad27-pX8	62 ± 14 (35)	12 ± 3 (5)
rad27Δc	200 ± 38	49 ± 20

Mutation to canavanine resistance for cells grown in omission media.

^aSD, standard deviation.

^bValues normalized to the RAD27 rates for empty vector (pRS424) or for POL30, as appropriate, are shown in parentheses. For all strains except RAD27, the pRS424.POL30 rate is significantly lower (P < 0.05) than the empty vector rate.

^cStrain SSL938.