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. 2009 Sep 17;15:1886–1896.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Müller cell activation following laser burn injury. Following retinal laser burn, eyes were enucleated, cryosectioned, and immunostained using the glial markers Cral-BP (A-C), GFAP (D-F), nestin (G-I), vimentin (J-L), and GS (M-O). Cral-BP was upregulated at 24 and 48 h within the injury site (A-C). GFAP was upregulated at 48 h postinjury (F). Nestin was upregulated at 24 h and 48 h (G-I) postinjury. Vimentin and GS did not show a significant increase in expression at any time point (J-O). The scale bar represents 75 μm. Abbreviation: outer nuclear layer (ONL). Arrowheads indicate Muller cell processes.