Table 1. Mouse strain characteristics.

	WT			12/15-LO KO
	NC	HFD	Fold Change	NC	HFD	Fold Change
Whole body weight, g	26.4 (0.5)	31.2 (0.7) #		25.2 (0.9)	25.2 (0.8) *
Epididymal fat pad weight, g	0.32 (0.02)	0.78 (0.06) #	2.45 (0.20)	0.23 (0.01)	0.43 (0.06) #, *	1.89 (0.26), ns vs WT HFD
Epididymal fat pad mass, % body weight	1.20 (0.08)	2.49 (0.19) #	2.07 (0.16)	0.89 (0.04)	1.64 (0.18) #, *	1.84 (0.20), ns vs WT HFD
Fasting plasma glucose, mg/dL	160 (5)	174 (6)		177 (5)	202 (9) #, *
Fasting plasma insulin, ng/mL	0.51 (0.18)	2.28 (0.83) #		0.63 (0.22)	0.57 (0.18) *

Data are averages±standard error. 7–10 mice per group. * p<0.05 vs diet-matched WT, # p<0.05 vs strain-matched NC. ns - not significant.