. Author manuscript; available in PMC: 2010 Jan 8.

Published in final edited form as: J Med Chem. 2009 Jan 8;52(1):62–73. doi: 10.1021/jm800817h

Table 2.

Ratios of Uptake of [¹¹C]1 and [¹¹C]4 in Brain Regions-of-interest to Caudate at 85 min Postinjection in the Baseline Studies and Pretreatment Studies with Desipramine

	[¹¹C]1			[¹¹C]4

	Baseline	Desipramine dose (mg/kg)		Baseline	Desipramine dose (mg/kg)
		0.125	0.25		0.125
Thalamus	1.30	1.10	1.06	1.34	1.02
Midbrain	1.43	1.20	0.91	1.33	1.09
Pons	1.44	1.13	0.91	1.27	0.98
Cerebellum	1.25	1.04	0.79	1.05	0.81