Table 3.
Multivariate relationship between selenium and other risk factors with all-cause mortality in older adults.
| Characteristic | HR | 95% CI | p |
|---|---|---|---|
| Model 1 | |||
| Plasma selenium | p1 for trend | 0.001 | |
| Quartile 1 | 1.82 | 1.20–2.75 | 0.005 |
| Quartile 2 | 1.48 | 0.96–2.29 | 0.073 |
| Quartile 3 | 1.14 | 0.72–1.81 | 0.567 |
| Quartile 4 | 1.00 | – | – |
| Age (yrs) | 1.14 | 1.12–1.16 | <0.001 |
| Sex (female) | 0.55 | 0.43–0.72 | <0.001 |
| Model 2 | |||
| Plasma selenium | p1 for trend | 0.004 | |
| Quartile 1 | 1.62 | 1.06–2.43 | 0.024 |
| Quartile 2 | 1.42 | 0.94–2.18 | 0.092 |
| Quartile 3 | 1.09 | 0.68–1.74 | 0.729 |
| Quartile 4 | 1.00 | – | – |
| Age (yrs) | 1.11 | 1.09–1.14 | <0.001 |
| Sex (female) | 0.53 | 0.39–0.70 | <0.001 |
| Education (yrs) | 0.97 | 0.93–1.02 | 0.122 |
| Body mass index (kg/m2) | |||
| <18.5 | 2.10 | 1.39–3.17 | 0.0004 |
| 18.5–24.9 | 1.00 | – | – |
| 25.0–29.9 | 1.23 | 0.84–1.57 | 0.475 |
| ≥30 | 1.16 | 0.78–1.72 | 0.458 |
| Total energy intake (kcal/day) | 1.00 | 1.00–1.00 | 0.368 |
| Congestive heart failure | 1.38 | 1.20–1.59 | <0.001 |
| Peripheral artery disease | 1.10 | 0.90–1.35 | 0.339 |
| Chronic obstructive pulmonary disease | 1.23 | 0.94–1.64 | 0.122 |
| Stroke | 1.25 | 1.04–1.49 | 0.015 |
| Parkinson’s Diseases | 1.35 | 0.87–2.09 | 0.185 |
1
p for trend obtained by considering selenium quartile level as ordinal variable.