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Changes in size a) and corresponding cumulative DOX release b) for the drug-loaded micelles (eq. 100 ug/ml) as a function of pH under in vitro conditions at 37°C over a period of 24 hr, including a release profile of free DOX (100 ug/ml) as a control. The hollow data points in Figure 8.a indicate the values were not precisely determined since they were beyond the measurement limit of the instrument. The release of free DOX was measured at pH 6.0.
