Figure 7.

A radial tree graph showing clustering at different levels. There are ten main branches, each representing one of the ten nodes at the first clustering level. Arrows indicate hierarchical connectivity determined after clustering; orange arrows indicate that the cluster center is preserved from one level to the next. Nodes are scaled so their area is proportional to their relative size: this is emphasized with nodes colored increasingly green as they are larger, and increasingly red as they are smaller. Nodes are annotated by a single letter: W, Watson-Crick base-pair; P, non-canonical base-pair; S, stacked; D, diagonal interaction; I, tertiary packing interaction; C, connected in chain; N, not connected in chain; A, platform, similar to an A-platform. On the outside are displayed the representative structures of the Size-10 Library; these correspond to the parent nodes of the ten main branches. The borders of the structural images are colored to match the colors used in Figure 9 and structures are oriented in consistent fashion with the view across the Watson-Crick binding face of the first nucleotide (orange), with its base perpendicular to the plane of the paper. The outermost nodes corresponding to the Size-30 Library are numerically labeled corresponding to Table 1.