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. Author manuscript; available in PMC: 2009 Sep 18.
Published in final edited form as: J Mol Biol. 2005 Aug 5;351(1):26–38. doi: 10.1016/j.jmb.2005.06.024

Figure 9.

Figure 9

Two-dimensional representation of the Size-50 Library in a space defined by the RMSD between library doublets. Nodes are colored based on the ten main branches that are rooted to the Size-10 Library; they are annotated in the same manner as in Figure 7. Colors of nodes match the color of the border of the structural images seen in Figure 7. We have shaded regions that contain nodes of similar structure, revealing four main classes: (1) stacked structures (S) at the bottom of the Figure; (2) generic connected structures (C) at the left of the Figure; (3) paired and diagonal structures (W, D and P) at the right side of the Figure; (4) everything else, which includes generic non-connected structure (N), tertiary interactions (I) and platform motifs (A).

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