FIGURE 4.
Low magnification of diseased corneas stained for some ECM components. INTACS channels of ~200 μm in diameter have irregular edges and display deposits of studied ECM proteins around them (collagens III and XIV and fibrillin-1); distant corneal stroma is not compromised. In case of post-LASIK, INTACS remnant (INT) is seen in the channel. E, epithelium; s, stroma; arrows point to the Descemet membrane (DM); KC-1, case 1 with keratoconus. INTACS channels are marked by asterisks. Bar = 150 μm.