Figure 7. Effects of Tempol and deferoxamine on flow-induced vasodilatation in soleus muscle arterioles of young and old, SED and ET rats.
A, neither Tempol or deferoxamine, an iron chelator, reduced flow-induced vasodilatation in young SED. B, Tempol reduced and Tempol + deferoxamine improved flow-induced vasodilatation in old SED. C, Tempol reduced and Tempol + deferoxamine restored flow-induced vasodilatation in young ET. D, Tempol reduced flow-induced vasodilatation; however, Tempol + deferoxamine only partially restored flow-induced vasodilatation in the old ET. *P < 0.05 vs. control response.