Table 4.
Risk of Late Menarche in Survivors of Childhood CNS Tumors and Acute Lymphoblastic Leukemia: Multivariate Model✶
| Odds Ratio | 95% CI | |
|---|---|---|
| Age at Diagnosis | ||
| 5-9 | 0.67 | 0.25-1.73 |
| 10-20 | 3.14 ✶ | 1.31-7.66 |
| 0-4 | 1.00 | |
| RT Dose to H-P axis † | ||
| <=20 Gy | 1.00 | 0.18-5.58 |
| >20 - <=30 Gy | 3.17 | 0.96-14.39 |
| >30 - <=50 Gy | 6.34 | 0.81-60.51 |
| >50 Gy | 13.24 ✶ | 1.81-142.17 |
✶
Controling for primary cancer diagnosis and spinal RT exposure
* = value is statistically significant (p<.05)
RT = Radiation Therapy, H-P Axis = Hypothalamic-Pituitary Axis, Gy = Grey, CI = Confidence Interval