Figure 2.
Identical deletions are associated with diverse phenotypic outcomes. Oligonucleotide array CGH results are depicted for (A) chromosome 1q21.1 (hg18, chr1: 143,000,000–145,500,000) and (B) chromosome 15q13.3 (hg18, chr15: 28,000,000–31,000,000). X-axis, genomic location; y-axis, log2 ratio of fluorescence intensity; red and green bars represent log2 ratio less than or greater than 1.5 standard deviations from the mean, respectively. Clinical features for the individuals shown are listed to the left of the array CGH results for that individual. Segmental duplication blocks are depicted by orange/yellow/gray bars at the top (90–94.9%, 95–99% and >99% sequence identity respectively); genes are shown below each figure.