Figure 1. Dendritic cell and macrophage populations in human skin during steady-state and inflammation.
Non-inflamed skin contains epidermal Langerhans cells, CD1c/ BDCA-1+ resident dermal DCs, plasmacytoid DCs, and macrophages. In addition, inflamed skin contains a large population of myeloid “inflammatory” DCs. Common markers used to identify these leukocyte populations are indicated.