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. Author manuscript; available in PMC: 2009 Sep 18.

Published in final edited form as: Science. 2008 Aug 21;322(5898):104–110. doi: 10.1126/science.1158684

Fig. 1 — Evaluation of S. cerevisiae protein-protein interaction datasets. (A) Number of interactions reported in various large-scale S. cerevisiae protein-protein interaction datasets. (B) Schema of pipeline used to assemble binary positive and random reference sets. (C) Fraction of a random sample of interactions from each dataset confirmed by Y2H and PCA. (D) Fraction of positives in each dataset calculated using MIPS and Binary-GS. (Error bars indicate standard error).

Fig. 1 — Evaluation of S. cerevisiae protein-protein interaction datasets. (A) Number of interactions reported in various large-scale S. cerevisiae protein-protein interaction datasets. (B) Schema of pipeline used to assemble binary positive and random reference sets. (C) Fraction of a random sample of interactions from each dataset confirmed by Y2H and PCA. (D) Fraction of positives in each dataset calculated using MIPS and Binary-GS. (Error bars indicate standard error).