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. Author manuscript; available in PMC: 2009 Sep 18.
Published in final edited form as: Nat Neurosci. 2009 Jun 7;12(7):857–863. doi: 10.1038/nn.2334

Figure 7.

Figure 7

NMDA-induced superoxide production in cell bodies and dendrites. Confocal images of mouse CA1 hippocampus after immunostaining for the neuronal marker MAP2 and the lipid oxidation product 4HNE. Brains were harvested 30 min after stereotactic injections with NMDA. 4HNE formation was evident in the neuronal cell bodies of the stratum pyramidale (SP) and in the dendrites extending from the stratum radiatum (SR). 4HNE formation was markedly reduced in p47phox−/− mice. Scale bar represents 40 µm. Images are representative of three mice from each group.