TABLE 1.
Summary of chemosensory index (CSI) and excitatory or inhibitory chemosensory drive (CD) values for each nucleus
| Nucleus | Synaptic Blockade | Activated | Unchanged | Inhibited | eCSI | eCD | iCSI | iCD | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| A. Chemosensory nuclei | ||||||||||||||||
| Locus coeruleus | − | 103 ± 71% | 42 ± 29% | 0 | 8.6 ± 0.4 | 6.1 | — | — | ||||||||
| + | 44 ± 38% | 70 ± 61% | 1 ± 1% | 5.8 ± 0.4 | 2.2 | — | — | |||||||||
| Solitary tract | − | 8 ± 14% | 44 ± 77% | 5 ± 9% | 7.0 ± 1.3 | 1.0 | −4.7 ± 0.4 | −0.5 | ||||||||
| + | 95 ± 47% | 91 ± 45% | 15 ± 7% | 5.2 ± 0.3 | 2.4 | −5.4 ± 0.5 | −0.8 | |||||||||
| Retrotrapezoid | − | 18 ± 21% | 53 ± 62% | 14 ± 16% | 8.4 ± 1.2 | 1.8 | −7.6 ± 1.0 | −1.3 | ||||||||
| + | 25 ± 23% | 64 ± 59% | 19 ± 18% | 4.3 ± 0.2 | 1.0 | −6.3 ± 0.4 | −1.3 | |||||||||
| Lateral paragiganto- | − | 7 ± 11% | 54 ± 86% | 2 ± 3% | 3.6 ± 0.2 | 0.4 | −4.1 ± 0.4 | −0.2 | ||||||||
| cellular | + | 11 ± 16% | 57 ± 84% | 0 | 4.0 ± 0.2 | 0.6 | — | — | ||||||||
| Raphé obscurus | − | 25 ± 16% | 125 ± 78% | 11 ± 7% | 4.4 ± 0.2 | 0.7 | −4.0 ± 0.1 | −0.6 | ||||||||
| + | 12 ± 20% | 14 ± 23% | 34 ± 56% | 9.8 ± 2.6 | 2.1 | −11.4 ± 0.8 | −6.4 | |||||||||
| Raphé pallidus | − | 0 | 82 ± 100% | 0 | — | — | — | — | ||||||||
| + | 24 ± 18% | 108 ± 81% | 2 ± 1% | 5.7 ± 0.5 | 1.0 | −3.9 ± 0.5 | −0.3 | |||||||||
| B. Nonchemosensory nuclei | ||||||||||||||||
| Giganto-cellular | − | 34 ± 41% | 38 ± 46% | 10 ± 12% | 7.7 ± 0.6 | 3.2 | −5.2 ± 0.5 | −0.8 | ||||||||
| reticular | + | 0 | 29 ± 66% | 15 ± 34% | — | — | −5.5 ± 0.4 | −2.4 | ||||||||
| Spinal trigeminal | − | 48 ± 53% | 34 ± 38% | 8 ± 9% | 8.6 ± 0.5 | 4.6 | −8.7 ± 0.3 | −1.0 | ||||||||
| + | 9 ± 7% | 109 ± 91% | 2 ± 2% | 3.8 ± 0.3 | 0.3 | −3.7 ± 0.2 | −0.2 | |||||||||