Table 4.

Maternal coffee and tea consumption during pregnancy and central nervous system tumours.

	Controls n = 1681	All CNS Tumours n = 209			PNET n = 100			Ependymomas n = 33			Astrocytomas n= 26			Other gliomas n = 45
		n	OR	95% CI	n	OR	95% CI	n	OR	95% CI	n	OR	95% CI	n	OR	95% CI
Coffee
No	639	76	1.0	reference	37	1.0	reference	11	1.0	reference	11	1.0	reference	15	1.0	reference
Yes	1042	133	1.0	[0.8–1.4]	63	1.0	[0.6–1.5]	22	1.3	[0.6–2.8]	15	0.8	[0.4–1.7]	30	1.1	[0.6–2.1]
≤3 cups/day	923	113	1.0	[0.7–1.3]	57	1.0	[0.6–1.5]	17	1.2	[0.5–2.5]	13	0.8	[0.3–1.8]	23	1.0	[0.5–1.9]
> 3 cups/day	119	20	1.4	[0.8–2.4]	6	0.9	[0.4–2.2]	5	2.7	[0.9–8.1]	2	0.9	[0.4–2.2]	7	2.3	[0.9–5.9]
Tea
No	962	108	1.0	reference	54	1.0	reference	15	1.0	reference	14	1.0	reference	24	1.0	reference
Yes	719	101	1.3	[0.9–1.7]	46	1.1	[0.8–1.7]	18	1.6	[0.8–3.1]	12	1.2	[0.5–2.5]	21	1.2	[0.6–2.1]
≤1 cup/day	491	66	1.2	[0.9–1.7]	28	1.0	[0.6–1.7]	9	1.1	[0.5–2.6]	8	1.1	[0.5–2.7]	17	1.4	[0.7–2.9]
> 1 cup/day	228	35	1.4	[0.9–2.1]	18	1.4	[0.8–2.4]	9	2.5	[1.1–5.9]	4	1.2	[0.4–3.8]	4	0.7	[0.2–2.0]
Coffee and tea (cups/day)
None	353	37	1.0	reference	19	1.0	reference	4	1.0	reference	4	1.0	reference	10	1.0	reference
Coffee ≤ 3 and tea ≤ 1	919	112	1.2	[0.8–1.7]	51	1.0	[0.6–1.7]	18	1.8	[0.6–5.4]	17	1.7	[0.6–5.0]	22	0.8	[0.4–1.7]
Coffee > 3 and tea ≤ 1	104	15	1.4	[0.7–2.6]	5	0.9	[0.3–2.6]	2	1.9	[0.3– 10]	1	0.8	[0.1–7.1]	7	2.2	[0.8–6.0]
Coffee ≤ 3 and tea > 1	210	28	1.3	[0.7–2.1]	15	1.3	[0.6–2.6]	6	2.6	[0.7–9.5]	3	1.3	[0.3–5.8]	4	0.6	[0.2–2.0]
Coffee > 3 and tea > 1	12	5	4.4	[1.5–13]	1	1.8	[0.2– 14]	3	23.1	[4.4–120]	1	8.5	[0.9– 84]	0	-	-

^aOR: Odds Ratios adjusted for age and gender,

^b95% Cl: 95% Confidence Interval