Table 5.

Maternal alcohol consumption during pregnancy and central nervous system tumours.

	Controls n = 1681	All CNS Tumours n = 209			PNET n = 100			Ependymomas n = 33			Astrocytomas n = 26			Other Gliomas n=45
		n	OR	95% CI	n	OR	95% CI	n	OR	95% CI	n	OR	95% CI	n	OR	95% CI
Any alcohol
No	1065	134	1.0	reference	60	1.0	reference	22	1.0	reference	18	1.0	reference	30	1.0	reference
Yes	616	75	0.9	[0.7–1.3]	40	1.1	[0.7–1.7]	11	0.9	[0.4–2.0]	8	0.8	[0.3–1.8]	15	0.8	[0.4–1.5]
< 1 glass/week	285	39	1.1	[0.7–1.6]	25	1.5	[0.9–2.4]	5	0.9	[0.3–2.3]	3	0.6	[0.2–2.2]	6	0.7	[0.3–1.7]
1 glass/week	136	14	0.8	[0.4–1.4]	8	1.0	[0.4–2.1]	2	0.8	[0.2–3.6]	1	0.4	[0.1–3.2]	2	0.5	[0.1–2.0]
2 glasses/week	70	9	1.0	[0.5–2.1]	2	0.5	[0.1–2.2]	1	0.8	[0.1–5.8]	2	1.7	[0.4–7.5]	4	2.0	[0.7–5.8]
≥ 3 glasses/week	125	13	0.8	[0.7–1.6]	5	0.7	[0.3–1.7]	3	1.3	[0.4–4.5]	2	1.0	[0.2–4.3]	3	0.8	[0.2–2.6]
Wine
No	1241	159	1.0	reference	74	1.0	reference	27	1.0	reference	20	1.0	reference	34	1.0	reference
Yes	440	50	0.9	[0.6–1.2]	26	0.9	[0.6–1.5]	6	0.7	[0.3–1.6]	6	0.9	[0.3–2.2]	11	0.9	[0.4–1.7]
Beer/cider
No	1474	177	1.0	reference	83	1.0	reference	31	1.0	reference	23	1.0	reference	36	1.0	reference
Yes	207	32	1.3	[0.8–1.9]	17	1.4	[0.8–2.5]	2	0.5	[0.1–2.0]	3	1.0	[0.3–3.2]	9	1.7	[0.8–3.6]
Spirits
No	1411	181	1.0	reference	82	1.0	reference	27	1.0	reference	26	1.0	reference	42	1.0	reference
Yes	270	28	0.8	[0.5–1.2]	18	1.1	[0.6–1.9]	6	1.3	[0.5–3.2]	0	-	-	3	0.3	[0.1–1.1]
No alcohol	1065	134	1.0	reference	60	1.0	reference	22	1.0	reference	18	1.0	reference	30	1.0	reference
Wine only	201	24	0.9	[0.6–1.5]	10	0.8	[0.4–1.7]	3	0.8	0.4–2.6]	5	1.5	[0.5–4.2]	6	1.0	[0.4–2.5]
Beer/cider only	65	10	1.3	[0.6–2.5]	3	0.8	[0.3–2.8]	2	1.5	[0.4–6.8]	2	2.0	[0.4–6.8]	3	1.7	[0.5–5.7]
Spirits only	95	11	0.9	[0.5–1.7]	8	1.4	[0.6–3.0]	3	1.6	[0.5–5.7]	0	-	-	0	-	-
Wine and beer/cider	80	13	1.2	[0.7–2.3]	9	1.8	[0.9–3.9]	0	-	-	1	0.8	[0.1–5.9]	3	1.2	[0.4–4.1]
Wine and spirits	113	8	0.6	[0.3–1.2]	5	0.8	[0.3–1.9]	3	1.5	[0.4–5.0]	0	-	-	0	-	-
Beer/cider and spirits	16	4	2.0	[0.7–6.2]	3	3.4	[0.9–12]	0	-	-	0	-	-	1	2.0	[0.3–16]
Wine, beer/cider and spirits	46	5	0.8	[0.3–2.1]	2	0.7	[0.2–3.0]	0	-	-	0	-	-	2	1.3	[0.3–5.7]

^aOR: Odds Ratios adjusted for age and gender,

^b95% Cl: 95% Confidence Interval