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. Author manuscript; available in PMC: 2010 Oct 19.
Published in final edited form as: Physiol Behav. 2009 Jul 17;98(4):427–432. doi: 10.1016/j.physbeh.2009.07.007

Fig. 5.

Fig. 5

Light-induced Fos production in the suprachiasmatic nuclei of BALB/cJ and C57BL/6J mice. (A) Mice were subjected to acute exposure to light (~200 lux for 15 mins) at ZT10 of their original light-dark cycle (indicated by vertical arrows), a normally unresponsive time of the circadian cycle, following either a single-day 6-hr phase advance of the light-dark cycle or release to constant darkness. Activity rhythms were advanced by the phase shifts in the BALB/cJ mice (left panel), so that the acute light exposure occurred several hours after their apparent onset of activity. Shaded areas correspond to lights off. (B) Acute light exposure two days following a single 6-hr advance of the light cycle stimulated prominent stereotypical Fos production in cells of the ventrolateral suprachiasmatic nucleus (indicated by horizontal arrows) in all of the BALB/cJ but none of the C57BL/6J mice. (C) No Fos was detected in the suprachiasmatic nuclei of any of the mice when no acute light pulse was administered following a 6-hr phase advance. (D) Acute light exposure did not yield Fos production in any of the mice if not preceded by a single-day 6-hr phase shift. (3V= third ventricle; OC= optic chiasm)