Table 5.
Number of relevant articles retrieved with and without search filters
| Clinical question* | No of relevant articles retrieved | No of non-relevant articles retrieved† | |||||
|---|---|---|---|---|---|---|---|
| Clinician’s search alone | Clinician’s search with most sensitive renal content filter | Clinician’s search with most specific renal content filter | Clinician’s search alone | Clinician’s search with most sensitive renal content filter | Clinician’s search with most specific renal content filter | ||
| What are the effects of statins on change in kidney function and urinary protein excretion? (24 relevant articles) | 6 | 20 | 16 | 86 | 48 | 39 | |
| What is the impact of fenoldopam on acute kidney injury, patients’ mortality, and length of hospital stay in critically ill patients? (12 relevant articles) | 1 | 11 | 11 | 7 | 32 | 21 | |
| When tacrolimus is compared directly with ciclosporin in the treatment of kidney transplant recipients, what is the evidence on transplant outcomes, toxicity, and adverse effects? (63 relevant articles) | 10 | 60 | 60 | 18 | 20 | 15 | |
| What is the efficacy of low dose dopamine (<5 μg/kg of body weight per minute) compared with no therapy in patients with or at risk for acute renal failure? (52 relevant articles) | 6 | 15 | 12 | 13 | 16 | 15 | |
| How does intradermal v intramuscular hepatitis B vaccine compare regarding response rate among chronic kidney disease patients? (11 relevant articles) | 6 | 10 | 10 | 22 | 34 | 31 | |
*Five clinicians were asked to type in a PubMed search to answer a focused clinical question for which relevant articles were summarised in a recent systematic review.33-37 Each search was restricted to search dates provided in methods of each review. Search phrases as determined and typed in by clinicians were: “statins and kidney function”, “fenoldopam and acute kidney injury”, “‘kidney transplant outcome tacrolimus cyclosporin”, “low-dose dopamine and acute renal failure”, and “hepatitis b vaccination in chronic kidney disease”. Renal terms were removed when the clinician’s search was performed with renal content filters.
†Number of non-relevant articles retrieved is expressed per relevant article, rounded up to nearest whole number.