Fig. 2.

Growth of S. cerevisiae oar1Δ mutants expressing M. tuberculosis FabG1 or FabG4. Yeast oar1Δ cells expressing native mitochondrial 3-oxoacyl-ACP reductase (Oar1p positive control), native peroxisomal catalase A (Cta1p negative control), mitochondrially targeted FabG1 or mitochondrially targeted FabG4 were grown in liquid SD-Ura medium that selected for plasmid presence. Following serial dilution, cells were applied to solid (SD-Ura) glucose or (SCglycerol) glycerol media. The plates were incubated at 30°C until single colonies appeared and recorded photographically. The yPLM strains used were 37, 38, 41 and 43