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The correlation between NG and LC is weak in genomes of placental mammals. In general, larger chromosomes also tend to have more genes in mammals; however, many chromosomes significantly deviate from a constant NG/LC ratio, rendering the genome-wide trend much weaker in placental mammalian genomes than in all other genomes. The highest R2 value in a mammal was found for rat (R2 = 0.70) whose genome contains the smallest relative fraction of gene deserts
