Table 2.

Association detected with χ² tests on alleles and genotypes from the ICCSS

Gene (Role)	Marker	Minor Allele Freq.		HWE P-Value		χ2 P-Value
		Controls	Cases	Controls	Cases	Allele	Genotype
No gene	rs2549012	0.386	0.389	0.008	0.23	0.877	0.017
SPEC2 (prom)	rs3756295	0.373	0.36	0.023	0.548	0.538	0.078
PDZ-GEF2 (intron)	rs31251	0.395	0.381	0.039	0.113	0.514	0.027
ACSL6 (intron)	rs2240525	0.389	0.377	0.054	0.207	0.555	0.06
DTNBP1(intron)	rs16876738	0.12	0.094	0.32	0.817	0.062	0.172
DTNBP1(intron)	rs2005976	0.199	0.162	0.409	0.055	0.039	0.071
DTNBP1(intron)	rs760761	0.247	0.181	0.495	0.987	0.001a	0.002b

^aExceeds the threshold for significance for any single-locus test for either sample

^bExceeds the threshold for significance for tests within the ICCSS