Table 3.
APL and HBAT-e haplotype analysis for associated blocks in ISHDSF
| Analysis | Gene | Markers | Haplotype | Frequency | P-Value |
|---|---|---|---|---|---|
| APL | - | rs3914025-rs3846726-rs3916441 | T-A-A | 0.392 | 0.001 |
| APL | - | rs3846726-rs3916441-rs31400 | A-A-T | 0.356 | 0.025 |
| HBAT -e | - | rs3914025-rs3846726-rs3916441-rs31400 | T-A-A-T | 0.361 | 0.046 |
| HBAT -p | - | rs3914025-rs3846726-rs3916441-rs31400 | T-A-A-T | 0.361 | 0.038 |
|
| |||||
| APL | IL3 | rs31400-rs31480-rs40401 | T-C-C | 0.392 | 0.043 |
| APL | IL3 | rs40401-rs31481-rs2069803 | C-G-T | 0.341 | 0.011 |
| HBAT -e | IL3 | rs31400-rs31480-rs40401-rs31481-rs2069803 | T-C-C-G-T | 0.344 | 0.037 |
| HBAT -p | IL3 | rs31400-rs31480-rs40401-rs31481-rs2069803 | T-C-C-G-T | 0.344 | 0.032 |
|
| |||||
| APL | DTNBP1 | rs2005976-rs760761-rs2619522 | G-T-A | 0.158 | 0.045 |
| APL | DTNBP1 | rs760761-rs2619522-rs1018381 | T-A-C | 0.072 | 0.067 |
| HBAT -e | DTNBP1 | rs2005976-rs760761-rs2619522-rs1018381 | G-T-A-C | 0.091 | 0.057 |
| HBAT -p | DTNBP1 | rs2005976-rs760761-rs2619522-rs1018381 | G-T-A-C | 0.091 | 0.078 |