Table 1. Frequency of G191R PRSS2 variant in patients and controls.
Population | Patients | Controls | ||||||
---|---|---|---|---|---|---|---|---|
Mutation/Total | % | 95% CI | Mutation/Total | % | 95% CI | OR | P value | |
German | 19/1548 | 1.2 | [0.7-1.8.] | 71/2019 | 3.5 | [2.7-4.3.] | 0.34 | 0.000012 |
European (w/o German) | 13/918 | 1.4 | [0.7-2.2] | 149/4440 | 3.4 | [2.8-3.9] | 0.41 | 0.00097 |
European (all) | 32/2466 | 1.3 | [0.9-1.7] | 220/6459 | 3.4 | [3.0-3.8] | 0.37 | 1.1 × 10-8 |
Number of mutations and sample sizes, frequencies of mutations, 95 % confidence intervals (95% CI) of the frequencies for patients and for controls, odds ratio (OR), and the P-value of the Fisher’s Exact Test.