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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Dev Cell. 2009 Sep;17(3):425–434. doi: 10.1016/j.devcel.2009.08.005

Figure 4. H3K27me3 is linked to localized repression patterns.

Figure 4

H3K27me3 marks genes spatially regulated along the dorso-ventral and animal-vegetal axis. Xenopus embryo explant microarray data (animal and vegetal cap, dorsal and ventral marginal zone) was compared to H3K4me3 and H3K27me3 occupancy at promoters of differentially regulated genes. H3K27me3 is enriched at 5′ ends of genes which are at least 2-fold higher expressed in the vegetal side of the embryo compared to the animal cap. Genes which are either preferentially expressed (2-fold difference) at the dorsal or at the ventral side of the embryo are also enriched for H3K27me3 at their 5′ end. Number of genes in these groups: animal 211; vegetal 201; dorsal 33; ventral 22; no differential expression 2955.