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. Author manuscript; available in PMC: 2010 Jul 31.
Published in final edited form as: Circ Res. 2009 Jul 9;105(3):295–303. doi: 10.1161/CIRCRESAHA.109.194613

Figure 2.

Figure 2

SMS2 deficiency significantly increased macrophage cholesterol efflux in vivo. SMS2 KO or WT bone marrow-derived macrophages were loaded with cholesterol by incubation with acetylated LDL and [3H]cholesterol. Labeled macrophages were injected intraperitoneally into WT mice. Plasma was collected at 12, 24, and 48 hours. Feces were collected at 24 and 48 hours. All were analyzed for tracer counts. Values are mean ± SD, N=5. *P<0.01.