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. 2008 Aug;90(8):1197–1206. doi: 10.1016/j.biochi.2008.01.015

Fig. 5.

Fig. 5

(A) Changes in single-molecule FRET histograms during the opening of the DNA quadruplex by hybridization to 7 nM III. The ‘zero’ peak at t = 0 has been subtracted from all histograms for clarity. The experiment was carried out at 20 °C in 100 mM NaCl and 10 mM Tris–HCl (pH 7.4). (B) Kinetic traces for the low- and high-FRET subpopulations. Data were fit to a single exponential. Copyright (2003) National Academy of Sciences of the United States of America [57].