Skip to main content
. Author manuscript; available in PMC: 2009 Sep 21.
Published in final edited form as: Nature. 2008 Apr 30;453(7193):415–419. doi: 10.1038/nature06893

Figure 2. A conformational change between CSP-A and CSP-B: implication for packing and sliding of the dsRNA genome.

Figure 2

a, Atomic model of CSP-A, coloured from blue at the N terminus to red at the C terminus. b, Close-up view of the CSP-A (blue) and CSP-B (purple) density map, showing that an α-helix (the upper helix within the green density) in CSP-A transforms into part of a β-hairpin in CSP-B (the upper part in the yellow density). c, Density maps with Cα models, showing the conformational change between CSP-A (left) and CSP-B (right). One α-helix in CSP-A transforms into part of the β-hairpin in CSP-B (indicated by curved arrow). The changing path is also indicated by an empty arrow. d, A 10Å slab extracted from the two-fold map showing the ordered dsRNA genome with a ~27Å distance between the adjacent dsRNA strands (arrow). The dotted box indicates the A-spike plug all the way in the central chamber of the turret.