Table 4. Incidence of solicited adverse events reported by mother or carer four days day after the first administration of IPT.
| SP-AQ (N = 694) | DHA-PQ (N = 559) | SP-PQ (N = 454) | |
| Vomitted | 218 (31%) | 76 (14%) | 76 (17%) |
| <24 months | 26% (74/282) | 17% (36/210) | 21% (42/196) |
| Risk difference (95%CI) | Reference | −8.4 (−18, 1.6) | −5.6 (−16, 5) |
| ≥24 months | 35% (144/412) | 12% (40/348) | 13% (34/258) |
| Risk difference (95%CI) | Reference | −22.7 (−32, −14) | −22.1 (−32, −13) |
| Fever | 219 (32%) | 98 (18%) | 89 (20%) |
| <24 months | 28% (79/282) | 20% (42/210) | 19% (37/196) |
| Risk difference (95%CI) | Reference | −5.9 (−16.5, 4.7) | −8.3 (−19.6, 3) |
| ≥24 months | 34% (140/412) | 16% (56/348) | 20% (52/258) |
| Risk difference (95%CI) | Reference | −17 (−28, −5.5) | −13 (−25, −1.1) |
| Rash | 14 (2%) | 3 (0.5%) | 5 (1.1%) |
| Risk difference (95%CI) | Reference | −1.2 (−3.1, 0.6) | −0.8 (−2.8, 1.1) |
| Itching | 27 (3.9%) | 7 (1.3%) | 8 (1.8%) |
| Risk difference (95%CI) | Reference | −2.7 (−5.5, 0.1) | −2.4 (−5.4, 0.6) |
| Headache | 87 (13%) | 32 (5.7%) | 18 (4%) |
| Risk difference (95%CI) | Reference | −6.7 (−13.2, −0.1) | −8.7 (−15.6, −1.7) |
Intraclass correlation coefficients for each outcome were as follows: vomiting 0.067, fever 0.078, rash 0.024, itching 0.039, headache 0.072. Risk differences were adjusted for age, or presented stratified by age group when there was a signification interaction with age.